昆虫嗅觉结合蛋白研究进展

嗅觉结合蛋白是嗅觉系统的第一个参与者,主要表达在嗅觉外周系统淋巴液中,负责识别、结合和转运气味和信息素分子到达嗅觉受体.近些年,随着各种生物新技术的应用,大量昆虫嗅觉结合蛋白被鉴定出来,其各种不同功能得到揭示.本文对近年来嗅觉结合蛋白的分子特征、蛋白结构、功能和应用等方面的研究进展进行总结和综述.总的来说,嗅觉结合蛋白...

Research progress of olfactory binding proteins in insects

As the first participant in the olfactory system, olfactory binding proteins are mainly expressed in the hemolymph of peripheral olfactory system and play roles in recognizing, binding and transporting odors or pheromones to odor receptors. In recent years, with the application of novel modern biological technology, more olfactory binding proteins have been identified, and their diverse functions have been revealed. In this article, we summarized the research progress in the molecular characteristics, structure, functions and application of olfactory binding proteins in recent years. Generally, olfactory binding proteins are classified into three families, odorant binding proteins (OBPs), chemosensory proteins (CSPs) and Niemann-Pick type C2 proteins (NPC2). Based on the α-helix and β-sheet, olfactory binding proteins form stable globular structure, which is beneficial for them to adapt to a variety of environments and tasks. And diverse functions of olfactory binding proteins are particularly important for insect physiology and behavior. Nowadays, olfactory binding proteins are used in biological control, variety selection and breeding, biosensor making, and so on. This review provides references and some new ideas for further research on olfactory binding proteins in insects.