合成生物学改造微生物及生物被膜用于重金属污染检测与修复

随着工业化进程不断加快,重金属污染日益加剧,尤其是水体的重金属污染,已严重威胁人类健康,迫切需要进行有效的污染修复.相比传统物理和化学修复,生物修复具有绿色环保和可持续性的特点.因为微生物生长繁殖迅速、生物被膜具有动态可调节和环境适应性好等特点,使其能更好耐受胁迫环境,在环境修复中有重要作用.合成生物学改造微生物及生物...

A Review on Bioremediation and Detection of Heavy Metal Pollution by Synthetic Biological Engineered Microorganisms and Biofilms

With the development of industrialization, heavy metal pollution has become a severe environmental hazard,in particular its pollution to water systems and consequently endangering human health,making its remediation an urgent issue. Compared with traditional physical and chemical remediation,bioremediation is green and sustainable. Microorganisms and microbial biofilms play an important role in bioremediation due to their rapid growth,intrinsic nature for dynamic adaption to environments and consequent tolerance to environmental stresses. Synthetic biology has provided a methodology for engineering and reprograming microorganisms and biofilms with robustness for more efficient degradation of environmental pollutants including heavy metals. This review summarizes the current status of heavy metal pollution,the bioremediation mechanism and research progress of microbial remediation,with a focus on the development of functional biofilms engineered by synthetic biology and their applications in bioremediation for heavy metal Pb,Hg,Cd and others. At the end,this review highlights the perspectives for bioremediation of heavy metal pollution.