Increased amounts of hybrid (heavy/heavy) DNA in Bloom's syndrome fibroblasts |
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| Authors: | R Waters J D Regan J German |
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| Institution: | Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830 USA;The New York Blood Center, New York, New York 10021 USA |
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| Abstract: | The nuclear DNA of fibroblasts from patients suffering with Bloom's syndrome, density labeled for less than one round of DNA replication to give heavy/light molecules, was examined for spontaneous amounts of heavy/heavy DNA (hybrid DNA). When compared to normal fibroblasts the Bloom's syndrome cells exhibited a sixfold increase in such DNA. |
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| Keywords: | BS Bloom's syndrome hybrid DNA heavy/heavy DNA |
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