Theileria sergenti proliferates in SCID mice with bovine erythrocyte transfusion. |
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| Authors: | M Tsuji K Hagiwara K Takahashi C Ishihara I Azuma W A Siddiqui |
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| Affiliation: | School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan. |
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| Abstract: | The unavailability of in vitro or in vivo experimental systems has been the major factor hampering the progress of research studies on Theileria sergenti, causative agent of theileriosis, a major disease of cattle in Japan. We report the first successful propagation of T. sergenti in SCID mice into which uninfected bovine erythrocytes (Bo-RBC) were supplied periodically. The infectivity of T. sergenti proliferated in an SCID mouse was ascertained by successful transfer of infection into another SCID mouse into which uninfected Bo-RBC were supplied periodically. |
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