Synovial cytokine mRNA expression during arthritis triggered by CpG motifs of bacterial DNA |
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Authors: | Guo-Min Deng Andrej Tarkowski |
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Affiliation: | 1. Department of Rheumatology, University of G?teborg, G?teborg, Sweden
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Abstract: | Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important immunomodulator during the development of joint inflammation. |
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