Intragenic suppression: Stalker,a retrovirus-like transposable element,can compensate for a deficiency at the cut locus of Drosophila melanogaster |
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Authors: | V A Mogila A B Ladvishenko O B Simonova T I Gerasimova |
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Institution: | (1) Institute of Gene Biology, Academy of Sciences of the USSR, Vavilov st., 34/5, 117908 Moscow, Russia |
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Abstract: | A number of mutations at the cut locus were induced by non-precise exision of a silent P-element insertion which resulted in deletions at the regulatory region of the locus. Unexpectedly, a reversion of one of these mutations was found, which appears as a result of insertion of Stalker (a retrovirus-like mobile element) near the 1.3 kb deletion. Thus an insertion of a retrovirus-like mobile element can suppress the deficiency at the regulatory region of a gene. |
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