Growth rate and rupture rate of unruptured intracranial aneurysms: a population approach

Background  

Understanding aneurysm growth rate allows us to predict not only the current rupture risk, but also accumulated rupture risk in the future. However, determining growth rate of unruptured intracranial aneurysms often requires follow-up of patients for a long period of time so that significant growth can be observed and measured. We investigate a relationship between growth rate and rupture rate and develop a theoretical model that can predict average behavior of unruptured intracranial aneurysms based on existing clinical data.