| 哺乳动物体细胞克隆及在动物转基因中的应用 |
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| 引用本文： | 李垚,陈学进.哺乳动物体细胞克隆及在动物转基因中的应用[J].中国实验动物学杂志,2010(1):1-5. |
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| 作者姓名： | 李垚 陈学进 |
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| 作者单位： | 上海交通大学医学院,上海200025 |
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| 摘 要： | 哺乳动物体细胞克隆及转基因技术,近些年发展迅速。尤其1997年‘多利’羊的诞生,对推动哺乳动物克隆及转基因技术的发展具有里程碑式的意义。本文介绍了哺乳动物体细胞克隆的方法,存在的问题和体细胞克隆的机理研究。对这些方法和研究理论进行了讨论,并探讨如何利用克隆技术进行转基因动物的制备。
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| 关 键 词： | 体细胞克隆 转基因动物 |
The Development of Mammalian Nuclear Transfer and Associated with the Transgenic Technology |
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| LI Yao,CHEN Xue-jin.The Development of Mammalian Nuclear Transfer and Associated with the Transgenic Technology[J].Chinese Journal of Laboratory Animal Science,2010(1):1-5. |
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| Authors: | LI Yao CHEN Xue-jin |
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| Institution: | (Department of Laboratory Animal Science,School of Medicine,Shanghai Jiao Tong University,Shanghai 200025,China) |
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| Abstract: | At present the development of mammalian nuclear transfer and transgenic animal is very quickly.In 1997,‘Dolly＇ was successfully cloned from adult cell,and it was a landmark development of clone.This review describes the recently developed animal clone techniques,problem and research mechanism.Every aspects are also discussed,as well as potentials of using clone method to develop transgenic animals. |
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| Keywords: | Somatic nuclear transfer Transgenic animal |
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