| 组织相容性复合体在实验鸡中的应用 |
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| 引用本文： | 高彩霞,韩凌霞,韩建林. 组织相容性复合体在实验鸡中的应用[J]. 中国实验动物学杂志, 2010, 0(2): 1-5 |
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| 作者姓名： | 高彩霞 韩凌霞 韩建林 |
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| 作者单位： | [1]中国农业科学院哈尔滨兽医研究所实验动物中心,哈尔滨150001 [2]甘肃农业大学动物科学技术学院,兰州730070 [3]中国农业科学院国家家畜研究所畜禽牧草遗传资源联合实验室,北京100094 |
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| 摘 要： | 鸡主要组织相容性复合体（MHC）基因位于鸡16号染色体上,具有高度的多态性。现已发现,不同MHC-B单倍体对各种疾病的抗性不同。本文主要介绍了鸡MHC的结构特点、鸡MHC与抗病性的关系、鸡MHC检测方法的研究进展以及其在鸡抗病育种中的应用前景。
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| 关 键 词： | 鸡MHC 抗病育种 遗传质量控制 |
Application of Major Histocompatibility Complex in Laboratory Chickens |
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| GAO Cai-xia,HAN Ling-xia,HAN Jian-lin. Application of Major Histocompatibility Complex in Laboratory Chickens[J]. Chinese Journal of Laboratory Animal Science, 2010, 0(2): 1-5 |
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| Authors: | GAO Cai-xia HAN Ling-xia HAN Jian-lin |
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| Affiliation: | 1.Laboratory Animal Center of Harbin Veterinary Research Institute,CAAS,Harbin 150001,China; 2.College of Animal Science and Technology of Gansu Agricultural University,Lanzhou 730070;3.CAAS-ILRI Joint Laboratory of Livestock and Forage Genetic Resources,Institute of Animal Science,Chinese Academy of Agricultural Sciences,Beijing 100094) |
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| Abstract: | Chicken major histocompatibility complex（MHC） has been a research focus for its high polymorphism and close relation with varying resistance against diseases.It is located on a microchromosome（chromosome 16）.It has been found that it has different resistance against diseases for different B haplotypes.The article gives a detailed introduction about structural characteristics,relation to diseases resistance,the progress in detection methods of chicken MHC,and the prospect of application of MHC in molecular breeding for disease resistance in chickens. |
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| Keywords: | Chicken MHC Breeding disease resistance Genetic quality control |
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