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Insertion Polymorphism of the CYP2E1 Gene in Patients with Infiltrative Pulmonary Tuberculosis from Bashkortostan |
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| Authors: | Bikmaeva A. R. Sibiryak S. V. Khusnutdinova E. K. |
| Affiliation: | (1) Russian Academy of Sciences, Institute of Biochemistry and Genetics, Ufa Research Center, Ufa, 450054, Russia;(2) Division of Experimental and Clinical Immunology, All-Russian Center of Eye and Plastic Surgery, Ufa, 450054, Russia |
| Abstract: | Insertion polymorphism Ins96 of the CYP2E1 promoter region was for the first time studied in three ethnic groups of Bashkortostan. Population-specific features of genotype and allele frequency distributions were observed. The CYP2E1 polymorphism was associated with infiltrative pulmonary tuberculosis in the Bashkortostan population. |
| Keywords: | pulmonary tuberculosis insertion polymorphism monooxigenase system cytochrome P450 apoptosis ethnogenomics |
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