Five new C21 steroidal glycosides from the stems of Marsdenia tenacissima |
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| Authors: | Hua Zhang Ai-Min Tan An-Yuan Zhang Rong Chen Shi-Bao Yang Xing Huang |
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| Affiliation: | Jiangsu Simcere Pharmaceutical R&D Co., Ltd., No. 699-18 Xuanwu Avenue, Xuanwu District, Nanjing 210042, PR China |
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| Abstract: | Five new C21 steroidal glycosides (1-5) were isolated from the stems of Marsdenia tenacissima. The chemical structures and relative configurations of the new compounds were elucidated by mass spectrometry and NMR spectroscopy. Cellular assay of these compounds showed that they are weak cytotoxic to various cell lines. |
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| Keywords: | Marsdenia tenacissima Steroidal glycosides Cytotoxic activity |
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