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Rapid synthesis of long chain fatty acid esters of steroids in ionic liquids with microwave irradiation: Expedient one-pot procedure for estradiol monoesters
Authors:Somdatta Deb
Affiliation:Laboratory of Organic Chemistry, University of Helsinki, A.I. Virtasen aukio 1, POB 55, FIN-00014 Helsinki, Finland
Abstract:We report the rapid synthesis (1 min) in high yield of fatty acid ester (FAE) derivatives of several steroids under microwave irradiation in an ionic liquid (IL). An expedient regioselective hydrolysis at C-3 of estradiol diesters is also reported.
Keywords:Microwave   Ionic liquid   Estradiol   DHEA   Testosterone   5α-Androstane-3β,17β-diol
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