Dehydration partitioned within core protoplast accounts for heat resistance of bacterial spores |
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| Authors: | Teofila C Beaman Tomihiko Koshikawa HStuart Pankratz Philipp Gerhardt |
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| Institution: | Unitéde Biochimie des Régulations Cellulaires, Départment de Biochimie et Génétique Moléculaire, Institut Pasteur, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France |
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| Abstract: | Abstract In Escherichia coli , adenosine 3',5'-cyclic monophosphate (cAMP) is excreted into the growth media. Making use of a phosphodiesterase as scavenger of extracellular cAMP we show that: (i) extracellular cAMP does not interfere with cellular functions; (ii) transient accumulation of cAMP, followed by its rapid excretion, elicits a severe repression of catabolic enzymes. |
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| Keywords: | Cyclic AMP excretion glucose effect transient repression |
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