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Experimental Dental Caries on Gnotobiotic Inbred Mice
Authors:Nobuko Maeda  Satoshi Arai  Akira Ozaki  Tsutomu Oowada  Akiko Takahashi  Hiroshi Fujita  Takeo Mizutani
Abstract:The purpose of this study in mono-infected gnotobiotic BALB/cA and C3H/HeN mice was to evaluate the cariogenicity of Enterococcus faecalis. The caries incidence and mean caries score in the BALB/cA mice were significantly higher than those in the C3H/HeN. In both of the mouse strains, the mean number of E. faecalis isolated from the cecum content was almost the same, however, the mean number of E. faecalis from the maxilla of BALB/cA was significantly higher than that of C3H/HeN. These results indicate that C3H/HeN has some factors that prevent E. faecalis from attaching to the tooth surfaces.
Keywords:gnotobiotic  inbred mice  cariogenicity  enterococcus faecalis
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