| KCNQ1基因及其编码钾通道的研究概况 |
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| 引用本文： | 陈莹,丁久平,徐涛. KCNQ1基因及其编码钾通道的研究概况[J]. 生物技术通讯, 2005, 16(5): 535-537 |
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| 作者姓名： | 陈莹 丁久平 徐涛 |
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| 作者单位： | 1. 华中科技大学,生命科学与技术学院生物物理与生物化学研究所,湖北,武汉,430074
2. 华中科技大学,生命科学与技术学院生物物理与生物化学研究所,湖北,武汉,430074;中国科学院,生物物理研究所,北京,100101 |
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| 摘 要： | 本文介绍了KCNQ1基因和其编码的通道蛋白的结构、生理学功能及电生理特点。归纳了围绕KCNQ1基因的热点研究方向和成果，并展望了未来的研究趋势。对基础医学上关心的KCNQ1基因突变与疾病的关系，及相关的病理药理学研究做了较为详细的介绍。
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| 关 键 词： | KCNQ1基因 钾离子通道 长QT综合征 电生理 |
| 文章编号： | 1009-0002(2005)05-0535-03 |
| 收稿时间： | 2005-01-24 |
| 修稿时间： | 2005-01-24 |
General Situation of Research about KCNQ1 Gene and the Potassium Channel it Codes |
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| CHEN Ying,DING Jiu-ping,XU Tao. General Situation of Research about KCNQ1 Gene and the Potassium Channel it Codes[J]. Letters in Biotechnology, 2005, 16(5): 535-537 |
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| Authors: | CHEN Ying DING Jiu-ping XU Tao |
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| Abstract: | KCNQ1 gene and the protein coded by it were introduced from the aspects of structure, physiology, and electrophysiology. The hot points and the main conclusions of researches about KCNQ1 were also summed up. Besides, the directions of related research were also presupposed. The relationship between KCNQ1 mutations and disease, as well as the pathophysiologic and pharmacological research related, were introduced in detail. |
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| Keywords: | KCNQ1 gene potassium ion channel long QT syndrome electrophysiology |
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