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Heparanase-mediated loss of nuclear syndecan-1 enhances histone acetyltransferase (HAT) activity to promote expression of genes that drive an aggressive tumor phenotype
Authors:Purushothaman Anurag  Hurst Douglas R  Pisano Claudio  Mizumoto Shuji  Sugahara Kazuyuki  Sanderson Ralph D
Institution:Department of Pathology, Center for Metabolic Bone Disease, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.
Abstract:
Keywords:Cancer Tumor Promoter  Cell Surface Enzymes  Histone Acetylase  Histone Modification  Membrane Enzymes  Proteoglycan Structure  Proteoglycan Synthesis  Heparanase  Syndecan-1
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