Progress toward the synthesis of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages. |
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| Authors: | J A Secrist P A Crooks J A Maddry R C Reynolds A S Rathore M S Ahktar J A Montgomery |
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| Affiliation: | Organic Chemistry Department, Southern Research Institute, Birmingham, AL 35255-5305. |
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| Abstract: | The synthesis of building blocks for the preparation of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages is described. Coupling conditions for the conversion of several of these monomers to dimers are also described. |
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