Detection of two immunochemically identical forms of mannan-binding lectin in the sea urchin <Emphasis Type="Italic">Strongylocentrotus nudus</Emphasis> |
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| Authors: | E V Shamshurina M G Eliseikina I Yu Petrova A A Bulgakov |
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| Institution: | 1.Institute of Marine Biology, Far East Branch,Russian Academy of Sciences,Vladivostok,Russia;2.Pacific Institute of Bioorganic Chemistry, Far East Branch,Russian Academy of Sciences,Vladivostok,Russia |
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| Abstract: | This study revealed a new lectin (MBL-SN) in the coelomic fluid of the sea urchin Strongylocentrotus nudus. Based on the peculiarities of molecular structure and carbohydrate specificity, MBL-SN can be assigned to the mannan-binding
lectin family. Using polyclonal monospecific rabbit antibodies against MBL-SN, the presence of MBL-SN in the sea urchin was
detected in two forms: a soluble form dissolved in the coelomic fluid and an extracellular matrix-bound form. The biosynthesis
site of this lectin may be one of the subpopulations of morula cells-coelomic fluid cells that perform heterosynthesis. Our
results demonstrate the similarity of the sea urchin lectin MBL-SN to the previously investigated MBLs of the holothurians
Cucumaria japonica and Apostichopus japonicus, and suggest a similarity to MBLs of vertebrates, which also have soluble and bound forms. |
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