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Development and validation of a whole genome amplification long-range PCR sequencing method for ADPKD genotyping of low-level DNA samples
Authors:Genyan Liu  Adrian Y Tan  Alber Michaeel  Jon Blumenfeld  Stephanie Donahue  Warren Bobb  Tom Parker  Daniel Levine  Hanna Rennert
Institution:1. Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY, USA;2. Department of Medicine, Weill Cornell Medical College, New York, NY, USA;3. The Rogosin Institute, New York, NY, USA;4. Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
Abstract:
Keywords:ADPKD  autosomal dominant polycystic kidney disease  PKD1  polycystic kidney disease 1  PKD2  polycystic kidney disease 2  HGs  human homologues  WGA  whole genome amplification  MDA  multiple displacement amplification  LR-PCR  long-range polymerase chain reaction  gDNA  genomic DNA
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