Four human Chromosome 3q and four human Chromosome 21 loci map onto sheep Chromosome 1q |
| |
| Authors: | T E Broad D J Burkin L M Cambridge P E Lewis D W Maher H A Ansari P D Pearce C Jones |
| |
| Institution: | (1) Gene Mapping Unit, AgResearch Grasslands Research Centre, Tennent Drive, Private Bag 1008, Palmerston North, New Zealand;(2) Eleanor Roosevelt Institute, University of Colorado Health Sciences Center, 1899 Gaylord Street, 80206 Denver, Colorado, USA;(3) Department of Biochemistry, Biophysics and Genetics, University of Colorado Health Sciences Center, 80206 Denver, Colorado, USA |
| |
| Abstract: | Eight new loci have been assigned to sheep Chromosome (Chr) 1q by use of a chromosomally characterized minipanel of sheep x hamster cell hybrids. Four loci, which have been mapped to the distal region of human Chr 3q, are ceruloplasmin (CP), sucrase isomaltase (SI), glucose transporter 2 (GLUT2), and ectopic viral integration site 1 (EVI1). The other four loci, on human Chr 21, include interferon alpha receptor (IFNAR); interferon inducible protein p78, murine (MX1); collagen type VI, alpha 1 (COL6A1); and S100 protein, beta polypeptide (S100B). All of these loci, except GLUT2 and MX1, have been mapped onto bovine Chr 1 or are syntenic with loci on this chromosome. The in situ localization of transferrin (TF) to sheep Chr 1q42-q45 confirms our previous assignment of this locus and independently anchors the eight new syntenic loci to sheep Chr 1q. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
