An acrasin-like attractant from yeast extract specific for Dictyostelium lacteum. |
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| Authors: | J M Mato P J van Haastert F A Krens T M Konijn |
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| Institution: | Cell Biology and Morphogenesis Unit, Zoological Laboratory, University of Leiden, Kaiserstraat 63, Leiden, the Netherlands |
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| Abstract: | The transition of the unicellular to the multicellular stage in Dictyostelium lacteum is not mediated by cyclic AMP. The attractant for aggregative amoebae of this cellular slime mold species was isolated from yeast extract and purified more than 1000-fold without a significant loss of activity. Several characteristics of the chemotactic molecule specific for D. lacteum are reported, and the presence of an inactivating enzyme has been demonstrated. |
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