Structural Proteins of Mammalian Oncogenic RNA Viruses: Murine Leukemia Virus Neutralization by Antisera Prepared Against Purified Envelope Glycoprotein |
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Authors: | R A Steeves Mette Strand and J T August |
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Institution: | 1Departments of Developmental Biology and Cancer and Molecular Biology, Division of Biological Sciences, Albert Einstein College of Medicine, Bronx, New York 10461 |
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Abstract: | Goat and rabbit antisera prepared against a purified Rauscher murine leukemia virus glycoprotein (gp69/71) rapidly neutralized spleen focus-forming virus in Rauscher and Friend virus preparations. Absorption studies revealed that most of the neutralizing activity of goat anti-Rauscher virus gp69/71 serum was directed against type- and group-specific determinants. |
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