The potential use of laser energy in the management of malaria |
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| Authors: | D E Rounds W Opel R S Olson I W Sherman |
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| Affiliation: | 1. Wellman Center for Photomedicine, Massachusetts General Hospital and Department of Dermatology, Harvard Medical School, Boston, MA 02114, United States;2. Affiliated faculty member of the Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA 02115, United States;1. Department of Physics and Astronomy, the University of Georgia, Athens, GA, USA;2. Nanoscale Science & Engineering Center, the University of Georgia, Athens, GA, USA;3. Department of Infectious Diseases, the University of Georgia, Athens, GA, USA;4. Center for Tropical and Emerging Global Diseases, the University of Georgia, Athens, GA, USA;1. Department of Medical Microbiology, Virology and Hygiene, University Medical Center Hamburg-Eppendorf, Hamburg, Germany;2. Department of Microbiology and Hospital Hygiene, Bundeswehr Hospital Hamburg, Hamburg, Germany;3. Institute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, Rostock, Germany;4. Bernhard Nocht Institute for Tropical Medicine Hamburg, Hamburg, Germany;5. Swiss Tropical and Public Health Institute, Basel, Switzerland;6. Faculty of Medicine, University Basel, Basel, Switzerland |
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| Abstract: | A feasibility study was conducted to illustrate that malarially parasitized erythrocytes from infected ducks and man, when treated with methylene blue and exposed to ruby laser energy, show a wavelength specific photolysis of only the parasitized erythrocytes. On the strength of this preliminary study, continuing investigation is being conducted to evaluate other parameters of laser treatment in the management of malaria in experimental animals. These studies suggest that it is feasible to design a protocol for the management of malaria in human patients. |
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