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Fine-Scale Genetic Diversity among Burkholderia pseudomallei Soil Isolates in Northeast Thailand |
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| Authors: | Jana M U'Ren Heidie Hornstra Talima Pearson James M Schupp Benjamin Leadem Shalamar Georgia Rasana W Sermswan and Paul Keim |
| Abstract: | Burkholderia pseudomallei soil isolates from northeast Thailand were genotyped using multiple-locus variable-number tandem repeat (VNTR) analysis (MLVA) and multilocus sequence typing (MLST). MLVA identified 19 genotypes within three clades, while MLST revealed two genotypes. These close genetic relationships imply a recent colonization followed by localized expansion, similar to what occurs in an outbreak situation. |
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