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Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model
Authors:Hazal B. Kose  Nicolai B. Larsen  Julien P. Duxin  Hasan Yardimci
Affiliation:1. Single Molecule Imaging of Genome Duplication and Maintenance Laboratory, The Francis Crick Institute, NW1 1AT London, UK;2. Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark
Abstract:
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  • Keywords:eukaryotic DNA replication  CMG  replicative helicase  DNA-protein crosslink  single-molecule imaging  steric exclusion
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