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AMPK Promotes Xenophagy through Priming of Autophagic Kinases upon Detection of Bacterial Outer Membrane Vesicles
Authors:Truc T Losier  Mercy Akuma  Olivia C McKee-Muir  Nicholas D LeBlond  Yujin Suk  Reham M Alsaadi  Zhihao Guo  Ryan Reshke  Subash Sad  François-Xavier Campbell-Valois  Derrick J Gibbings  Morgan D Fullerton  Ryan C Russell
Institution:1. Department of Cellular and Molecular Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada;2. Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 451 Smyth Road, Ottawa, ON K1H 8M5, Canada;3. University of Ottawa Center for Infection, Immunity, and Inflammation, Ottawa, ON K1H 8M5, Canada;4. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Pavillon D’Iorio Hall, 10 Marie Curie, Ottawa, ON K1N 6N5, Canada
Abstract:
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  • Keywords:autophagy  AMPK  mTOR  ULK1  VPS34  xenophagy  OMV  Salmonella  outer membrane vesicles
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