Walking motion of an overdamped active particle in a ratchet potential |
| |
Authors: | Kong-Ju-Bock Lee Chul Koo Kim Myung-Hoon Chung |
| |
Institution: | (1) Department of Physics, Ewha Womans University, Seoul, 120-750, Korea;(2) Korea Institute for Advanced Study, Seoul, 130-722, Korea;(3) Institute of Physics and Applied Physics, Yonsei University, Seoul, 120-749, Korea;(4) Department of Physics, Hongik University, Jochiwon, Choongnam, 339-701, Korea |
| |
Abstract: | An active particle can convert its internal energy into mechanical work. We study a generalized energy-depot model of an overdamped
active particle in a ratchet potential. Using well-known biological parameters for kinesin-1 and modeling ATP influx as a
pulsed energy supply, we apply our model to the molecular motor system. We find that our simple model can capture the essential
properties of the kinesin motor such as forward stepping, stalling, backward stepping, dependence on ATP concentration, and
stall force. Our model might be quite universal in the sense that it is able to describe dynamics of various types of motors
as long as realistic parameters for each motor species are adopted. |
| |
Keywords: | Active particle Kinesin Energy depot model |
本文献已被 SpringerLink 等数据库收录! |
|