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Immunologic and physico-chemical properties of hyperimmune antibodies with different affinities |
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| Authors: | Iu A Khavkin N G Bulygina A V Kornilova I S Khangil'dina V G Iakovlev |
| Abstract: | By immune chromatography fractions with various reaction rates of antigen precipitation and neutralization of toxin "in vivo" have been isolated from a common pool of antibodies. Antibodies of higher pI possessed an elevated relation of basis amino acid residues to unsubstituted dicarboxylic residues as well as greater affinity. The data suggest an important role of ion interaction and a general scheme of antigen and antibody molecules structure for immune reactions. |
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