The hydroxylation of steroidal ring D lactones by Cephalosporium aphidicola |
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| Institution: | 1. Department of Plant Physiology, University of Agriculture in Cracow, Podłużna 3, 30-239 Cracow, Poland;2. Institute of Plant Genetics, Polish Academy of Sciences, Strzeszyńska 34, 60-479 Poznań, Poland;3. The Franciszek Górski Institute of Plant Physiology, Polish Academy of Sciences, Niezapominajek 21, 30-239 Cracow, Poland;1. Department of Plant Physiology, University of Agriculture in Krakow, Podłużna 3, 30-239 Kraków, Poland;2. Institute of Plant Physiology, Polish Academy of Sciences, Niezapominajek 21, 30-239 Kraków, Poland;1. University of New Mexico, Department of Biology, Albuquerque, NM, USA;2. Sandia National Laboratories, Albuquerque, NM, USA;3. Concordia University, Centre for Structural and Functional Genomics, Montreal, QC, Canada;4. Novozymes Inc., Davis, CA, USA;5. DOE Joint Genome Institute, 2800 Mitchell Dr, Walnut Creek, CA, USA;1. Mycology Unit, Department of Medical Microbiology, Cerrahpasa Medical Faculty, 34098 Cerrahpasa, Istanbul, Turkey;2. Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, IISPV, Universitat Rovira i Virgili, E-43201 Reus, Spain;3. CBS-KNAW Fungal Biodiversity Centre, Utrecht, The Netherlands;4. Department of Neurology, Cerrahpasa Medical Faculty, 34098 Cerrahpasa, Istanbul, Turkey;5. Department of Infectious Disease and Clinical Bacteriology, Cerrahpasa Medical Faculty, 34098 Cerrahpasa, Istanbul, Turkey |
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| Abstract: | The microbiological hydroxylation of 17a-oxa-d-homo-5α-androstane-3,17-dione, the 3β-alcohol and the 13α-methyl analogue by Cephalosporium aphidicola takes place predominantly at C-7α in contrast to other hydroxylations by this organism. |
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