Glycans and neural cell interactions |
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Authors: | Kleene Ralf Schachner Melitta |
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Affiliation: | Zentrum für Molekulare Neurobiologie, Universit?t Hamburg, Martinistrasse 52, 20246 Hamburg, Germany. |
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Abstract: | Carbohydrate-carrying molecules in the nervous system have important roles during development, regeneration and synaptic plasticity. Carbohydrates mediate interactions between recognition molecules, thereby contributing to the formation of a complex molecular meshwork at the cell surface and in the extracellular matrix. The tremendous structural diversity of glycan chains allows for immense combinatorial possibilities that might underlie the fine-tuning of cell-cell and cell-matrix interactions. |
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