Identification and quantification of components in extracts of Uncaria tomentosa by HPLC-ES/MS |
| |
Authors: | Montoro P Carbone V Quiroz J de Dioz Zuniga De Simone F Pizza C |
| |
Institution: | Dipartimento di Scienze Farmaceutiche, Facoltá di Farmacia, Universitá di Salerno, Via Ponte don Melillo, 84084 Fisciano, Italy. pmontoro@unisa.it |
| |
Abstract: | The two main classes of secondary metabolites, alkaloids and quinovic acid glycosides, of Uncaria tomentosa (Willd.) DC. (Rubiaceae), a Peruvian plant commonly known as ‘uña de gato’, have been analysed. Separation of the alkaloidal fraction was achieved using a solid phase extraction method based on cationic exchange, and an analytical method employing HPLC‐ES/MS has been developed. Quantitative data for commercial wild bark, cultivated bark and leaves are reported. The analysis of quinovic acid glycosides was performed directly on the crude extract using both a fast analytical method based on ?ow injection ES/MS, and a more complete analytical technique using HPLC‐MS. Copyright © 2004 John Wiley & Sons, Ltd. |
| |
Keywords: | HPLC‐MS ES‐MS flow injection assay indole alkaloids quinovic acid glycosides Uncaria tomentosa |
本文献已被 PubMed 等数据库收录! |
|