Reversion of l-lysine inhibition of penicillin G biosynthesis by 6-oxopiperidine-2-carboxylic acid in Penicillium chrysogenum PQ-96 |
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| Authors: | W. Kurz↦kowski J. D. Kurz↦kowski J. Filipek J. Solecka W. Kurylowicz |
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| Affiliation: | (1) State Institute of Hygiene, Chocimska 24, 00-791 Warsaw, Poland;(2) Pharmaceutical Faculty, Medical Academy of Warsaw, Banacha 1, 02-097 Warsaw, Poland |
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| Abstract: | Summary 6-Oxopiperidine-2-carboxylic acid (OCA; cyclic  -aminoadipic acid) reverses the l-lysine inhibition of penicillin G production by Penicillium chrysogenum PQ-96. The reaction probably depends on the recovery of l--aminoadipic acid for penicillin G production from OCA.Offprint requests to: W. Kurz kowski |
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