DD1.5k, the gene preferentially expressed in bloodstream isolates of vancomycin-resistant Enterococcus faecium |
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Authors: | Kim Seung-Han Lee Dong-Gun Yoo Jin-Hong Choi Su-Mi Choi Jung-Hyun Shin Wan-Shik Lee Kyungwon Yong Dongeun Lee Wee Gyo Youn Byung-S Kang Moon-Won |
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Affiliation: | Clinical Research Institute, The Catholic University of Korea, Seoul, 150-713, Korea. |
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Abstract: | Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM. |
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