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DD1.5k, the gene preferentially expressed in bloodstream isolates of vancomycin-resistant Enterococcus faecium
Authors:Kim Seung-Han  Lee Dong-Gun  Yoo Jin-Hong  Choi Su-Mi  Choi Jung-Hyun  Shin Wan-Shik  Lee Kyungwon  Yong Dongeun  Lee Wee Gyo  Youn Byung-S  Kang Moon-Won
Institution:Clinical Research Institute, The Catholic University of Korea, Seoul, 150-713, Korea.
Abstract:Vancomycin-resistant Enterococcus faecium (VREFM) is becoming a threatening pathogen. We identified a gene called DD1.5K by differential display-PCR, which was preferentially expressed in the bloodstream isolates of VREFM. Due to its amino acid similarity to transfer complex protein, trsE, and tissue-specific expression, this gene may be involved in virulence of VREFM.
Keywords:
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