Designing secondary structures: 5-azidomethyl tetrahydrofuran-2-carboxylates as carbohydrate-derived dipeptide isosteres. |
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| Authors: | M D Smith G W Fleet |
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| Affiliation: | University of Oxford, The Dyson Perrins Laboratory, Oxford Centre for Molecular Sciences, UK. |
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| Abstract: | The potential of carbohydrate-like tetrahydrofuran frameworks as building blocks with predictable conformational propensities useful in the design and synthesis of novel peptidomimetic materials which adopt well-defined secondary structures is discussed. |
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