Breeding genetically modified rodents: tips for tracking and troubleshooting reproductive performance |
| |
| Authors: | Murray Kathleen A Parker Nancy Jean |
| |
| Institution: | Charles River Laboratories, Transgenic Services, Wilmington, MA 01887, USA. kmurray@criver.com |
| |
| Abstract: | Infertility or reduced fertility in genetically modified mouse strains represents a serious bottleneck for planned research projects. The authors describe simple methods for troubleshooting poor reproductive performance in breeding colonies and introduce various means of assisted reproduction that might be used to 'rescue' infertile lines. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
