BlastXtract2: Improving early exploration of (meta) genomes |
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| Authors: | Heleen de Weerd Bernd E van der Veen Marcus J Claesson |
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| Institution: | 1.Microbiology and Systems Biology, TNO, Zeist, The Netherlands;2.Genomics Core Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands;3.School of microbiology and alimentary pharmabiotic centre, university college cork, cork, Ireland |
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| Abstract: | To manage and intelligently mine the avalanche of genomic sequences intuitive and user-friendly graphical interfaces are required.
Here we present BlastXtract2 which exclusively facilitates early exploration of un-annotated genomic and metagenomic sequences.
Various formats of translated searches, including the commonly used BlastX, of multiple sequences against multiple protein
databases can be uploaded to a relational database server, which can be accessed via a locally installed web-server. There, an
intuitive GUI allows straightforward data-mining and enables quick detection of potential frameshifts and poorly sequenced or
assembled regions, thereby contributing in making BlastXtract2 a unique and valuable tool for early exploration of (meta)genomic
sequences.AvailabilitySource code, documentation and an online demo version are available at https://github.com/ ClaessonLab/BlastXtract2 |
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