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Tetrahedron DNA dendrimers and their encapsulation of gold nanoparticles
Affiliation:1. Key Laboratory of China''s Ethnic Languages and Information Technology of Ministry of Education, Northwest Minzu University, Lanzhou 730000, PR China;2. Key Laboratory of Streaming Data Computing Technologies and Application, Northwest Minzu University, Lanzhou 730030, PR China;3. School of Mathematics and Computer Science, Northwest Minzu University, Lanzhou 730030, PR China
Abstract:DNA dendrimers have achieved increasing attention recently. Previously reported DNA dendrimers used Y-DNA as monomers. Tetrahedron DNA is a rigid tetrahedral cage made of DNA. Herein, we use tetrahedron DNA as monomers to prepare tetrahedron DNA dendrimers. The prepared tetrahedron DNA dendrimers have larger size compared with those made of Y-DNA. In addition, thanks to the central cavity of tetrahedron DNA monomers, some nanoscale structures (e.g., gold nanoparticles) can be encapsulated within tetrahedron DNA monomers. Tetrahedron DNA encapsulated with gold nanoparticles can be further assembled into dendrimers, guiding gold nanoparticles into clusters.
Keywords:Tetrahedron  DNA dendrimer  Gold nanoparticle  Encapsulation  Self-assembly
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