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Synthesized quercetin derivatives stimulate melanogenesis in B16 melanoma cells by influencing the expression of melanin biosynthesis proteins MITF and p38 MAPK
Affiliation:1. Departamento de Química, Universidade Estadual de Maringá, Av. Colombo 5790, 87020-900 Maringá, PR, Brazil;2. Departamento de Biologia Geral, Universidade Estadual de Ponta Grossa, Av. Carlos Cavalcanti 4748, 84030-910 Ponta Grossa, PR, Brazil;1. School of Life Science and Technology, Yulin Normal University, Yulin 537000, PR China;2. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin 541006, PR China;1. Instituto de Química e Biotecnologia, Universidade Federal de Alagoas, 57072-970 Maceió, AL, Brazil;2. Instituto Federal de Educação, Ciência e Tecnologia da Bahia, 45075-265 Vitória da Conquista, BA, Brazil;3. Instituto do Meio Ambiente do Estado de Alagoas, 57017-020, Maceió, AL, Brazil;1. Department of Chemistry and Biochemistry, Northern Illinois University, 300 Normal Road, Dekalb, IL 60115, USA;2. Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 2460 Linden Lane, Silver Spring, MD 20910, USA;3. Discovery Biology, Eskitis Institute for Drug Discovery, Griffith University, 170 Kessels Road, Nathan, Queensland 4111, Australia;1. Department of Biotechnology, Daegu University, Kyongsan, Kyongbok 712-714, Republic of Korea;2. Metalloenzyme Research Group and School of Biological Sciences, Chung-Ang University, Anseong 456-756, Republic of Korea;1. Department of Botany and Microbiology, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451, Saudi Arabia;2. Department of Botany and Microbiology, Faculty of Science, University of Beni-Suef, 62511, Egypt
Abstract:
Keywords:B16 melanoma cells  Tyrosinase  TRP-1  Quercetin
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