Spontaneous inactivation of enkephalin. |
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Authors: | Z Vogel T Miron M Altstein M Wilchek |
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Institution: | Department of Microbiology, Meharry Medical College, Nashville, Tennessee 37208, USA |
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Abstract: | The role of isoleucyl-, valyl-, and leucyl-tRNA synthetases in attenuation of the operon was examined. The results indicate that the activities of isoleucyl- and valyl-tRNA synthetases are necessary to maintain attenuation of the operon. Leucyl-tRNA synthetase activity is nonessential for attenuation. These studies imply that uncharged tRNAIle and tRNAVal each may cause deattenuation. |
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