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Structural insights into eukaryotic ribosomes and the initiation of translation

Authors:	Felix Voigts-Hoffmann Sebastian Klinge Nenad Ban

Institution:	1. Division of Nephrology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea;2. Division of Cardiology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea;3. Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea

Abstract:	Download : Download high-res image (442KB) Download : Download full-size image Highlights? Overview of recent progress in the structural characterization of eukaryotic ribosomes and initiation complexes. ? Crystal structures, cryo-EM and biochemical data are combined to derive structural models of larger assemblies. ? Homology models of eukaryotic initiation complexes provide a starting point for future experiments.

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