| 广州地区74株淋球菌耐药性结果分析 |
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| 引用本文： | 曹文苓,黎小东,毕超,田歆,梁艳华,宋卫忠,林路洋,张锡宝. 广州地区74株淋球菌耐药性结果分析[J]. 中国微生态学杂志, 2009, 21(6): 553-554 |
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| 作者姓名： | 曹文苓 黎小东 毕超 田歆 梁艳华 宋卫忠 林路洋 张锡宝 |
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| 作者单位： | 广州市皮肤病防治所,广东,广州,510095 |
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| 摘 要： | 目的了解广州地区淋球菌对抗生素的耐药性及PPNG和TRNG的流行状况。方法用琼脂稀释法测定最低抑菌浓度（MIC）；用纸片碘量法检测β-内酰胺酶。结果74株淋球菌检出PPNG31株（41．9％）、TRNG19株（25．7％）、环丙沙星耐药率达97．3％，高度耐药株（MIC≥16mg／L）22株（29．7％），未发现对头孢三嗪、壮观霉素耐药的菌株，且抗菌活性最强。结论持续监测淋球菌的耐药性十分重要。
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| 关 键 词： | 淋球菌 最低抑菌浓度 PPNG TRNG 耐药性 |
Analysis of antibiotic resistance of Neisseria gonorrhoeae in Guangzhou |
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| CAO Wen-ling,LI Xiao-dong,BI Chao,TIAN Xin,LIANG Yan-hua,SONG Wei-zhong,LIN Lu-yang,ZHANG Xi-bao. Analysis of antibiotic resistance of Neisseria gonorrhoeae in Guangzhou[J]. Chinese Journal of Microecology, 2009, 21(6): 553-554 |
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| Authors: | CAO Wen-ling LI Xiao-dong BI Chao TIAN Xin LIANG Yan-hua SONG Wei-zhong LIN Lu-yang ZHANG Xi-bao |
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| Affiliation: | ( Guangzhou Institute of Dermatology, Guangzhou 510095, China) |
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| Abstract: | Objective To explore the antibiotic resistance and the prevalence of PPNG and TRNG in Guangzhou. Method Minimum inhibitory concentrations （MIC） to penicillin G, tetracycline, ciprofloxacin, ceftriaxone and spectiomycin were determined using the agar dilution method, and β-1actamase by paper iodin quantitative method. Result Of the total 74 strains of Neisseria gonorrhoeae produced β-lactamase, while 19 strains showed plasmid-mediated, high-level resistance to tetracycline（TRNG）. The resistant rates to ciprofloxacin was as much as 97.3% ;22 strains were highly resistant （ MIC 〉 = 16 rag/L）. No strains were found to be resistant to ceftriaxone and specitinomycin. Conclusion The study showed that it is important to successively monitor the antibiotic resistance, of Neisseriae gonorrhoeae. |
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| Keywords: | PPNG TRNG |
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