Iron metabolism during lactation and suckling in a marsupial, the quokka (Setonix brachyurus)

The iron status and transfer of iron through the milk during lactation were determined in a marsupial, the quokka, Setonix brachyurus. Lactating animals were not anaemic and had similar liver and spleen non-haem iron values to non-lactating female adult animals but about 40% less non-haem iron than male adults. The milk iron concentration was very high during the period of lactation when the young is confined to the pouch, averaging about 20 micrograms/ml (eight times the plasma iron concentration), but fell markedly at the time when the young commence to leave the pouch. Blood haemoglobin concentration increased during pouch life of the young to reach adult levels at about 180 days, and liver non-haem iron concentration increased during the same period to values nearly 20 times greater than in their mothers. After the young left the pouch the non-haem iron concentration fell rapidly to the adult level while haemoglobin concentrations were maintained. It is concluded that milk is an adequate source of iron during pouch life of the quokka and enables the animal to build up iron stores which can be utilized after leaving the pouch.