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A lead dependent ischemic episodes detection strategy using Hermite functions
Authors:T Rocha  S Paredes  P Carvalho  J Henriques  M Harris  J Morais  M Antumes  
Institution:a Instituto Superior de Engenharia de Coimbra, Departamento de Engenharia Informática e de Sistemas, Coimbra, Portugal;b Centro de Informática e Sistemas da Universidade de Coimbra, Portugal;c Philips Research Europe, Aachen, Germany;d Serviço de Cardiologia, Hospital de Santo André, Leiria, Portugal;e Centro de Cirurgia Cardiotóracia, Hospitais da Universidade, Coimbra, Portugal
Abstract:In this work a new strategy for automatic detection of ischemic episodes is proposed. A new measure for ST deviation based on the time–frequency analysis of the ECG and the use of a reduced set of Hermite basis functions for T wave and QRS complex morphology characterization, are the key points of the proposed methodology.Usually, ischemia manifests itself in the ECG signal by ST segment deviation or by QRS complex and T wave changes in morphology. These effects might occur simultaneously. Time–frequency methods are especially adequate for the detection of small transient characteristics hidden in the ECG, such as ST segment alterations. A Wigner–Ville transform-based approach is proposed to estimate the ST shift. To characterize the alterations in the T wave and the QRS morphologies, each cardiac beat is described by expansions in Hermite functions. These demonstrated to be suitable to capture the most relevant morphologic characteristics of the signal. A lead dependent neural network classifier considers, as inputs, the ST segment deviation and the Hermite expansion coefficients. The ability of the proposed method in ischemia episodes detection is evaluated using the European Society of Cardiology ST–T database. A sensitivity of 96.7% and a positive predictivity of 96.2% reveal the capacity of the proposed strategy to perform ischemic episodes identification.
Keywords:ECG analysis  Ischemic episodes detection  Hermite functions  Wigner–  Ville transform  Neural networks classifier
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