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Efficient nitrogen alkylation with carbohydrates
Authors:Hadzić Pavle  Vukojević Nada
Affiliation:Faculty of Sciences, Institut za hemiju, University of Novi Sad, Trg D. Obradovica 3, 21000, Serbia and Montenegro, Novi Sad, Yugoslavia. hadzic@eunet.yu
Abstract:Efficient nitrogen alkylation of various primary and secondary amines, including cyclic, heterocyclic and alkaloid type amines, with a sugar oxetane 3,5-anhydro-1,2-O-cyclohexylidene-alpha-D-xylofuranose is described. As a result, 5-amino-5-deoxy derivatives of xylofuranose were obtained in good yields.
Keywords:  smallcaps"  >d-Xylose   Sugar oxetane   Alkylation   Amphetamine   Demethylmorphine
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