<Emphasis Type="Italic">Dppa3 / Pgc7 / stella</Emphasis> is a maternal factor and is not required for germ cell specification in mice |
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| Authors: | Alex?Bortvin Mary?Goodheart Michelle?Liao Email author" target="_blank">David?C?PageEmail author |
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| Institution: | (1) Howard Hughes Medical Institute, Whitehead Institute, and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA |
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| Abstract: | Background In mice, germ cells are specified through signalling between layers of cells comprising the primitive embryo. The function
of Dppa3 (also known as Pgc7 or stella), a gene expressed in primordial germ cells at the time of their emergence in gastrulating embryos, is unknown, but a recent
study has claimed that it plays a central role in germ cell specification. |
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