Transposons as tools for enhancer trap screens in vertebrates |
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Authors: | Vladimir Korzh |
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Affiliation: | Institute of Molecular and Cell Biology, Biopolis Dr, Proteos, 138673, Singapore. vlad@imcb.a-star.edu.sg |
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Abstract: | DNA transposons are efficient tools in transgenesis and have therefore become popular in the analysis of the regulatory genome in vertebrates via enhancer trap screens. Here, I discuss recent progress in this field of research, with a focus on the application of one of these transposons, namely the medaka fish derived Tol2, to enhancer trapping in zebrafish, and how this approach compares with others that have a similar objective. |
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