Structure and genome organization of AFV2, a novel archaeal lipothrixvirus with unusual terminal and core structures |
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Authors: | Häring Monika Vestergaard Gisle Brügger Kim Rachel Reinhard Garrett Roger A Prangishvili David |
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Institution: | Unité de Biologie Moléculaire du Gène chez les Extrêmophiles, Institut Pasteur, rue Dr. Roux 25, 75724 Paris Cedex 15, France. |
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Abstract: | A novel filamentous virus, AFV2, from the hyperthermophilic archaeal genus Acidianus shows structural similarity to lipothrixviruses but differs from them in its unusual terminal and core structures. The double-stranded DNA genome contains 31,787 bp and carries eight open reading frames homologous to those of other lipothrixviruses, a single tRNA(Lys) gene containing a 12-bp archaeal intron, and a 1,008-bp repeat-rich region near the center of the genome. |
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