Studies on cytochrome c. 8. Synthesis of the protected hexadecapeptide (sequence 93-108) of Baker's yeast iso-1-cytochrome c

The synthesis is described of the protected hexadecapeptide corresponding to the C-terminal sequence 93–108 of baker's yeast iso-I-cytochrome c. The cysteine residue in position 107 of the natural sequence has been substituted by a threonine residue. The rationale of this substitution as well as the synthetic route to the preparation of the hexadecapeptide derivative is discussed.