The action of high doses of oestradiol on implantation and decidual reaction in the rat |
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| Authors: | P Sartor H Dupont MA Dupont AJ Duluc G Mayer |
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| Institution: | Laboratoire d''Histologie et Embryologie U.E.R. III Université de Bordeaux II, 33076 Bordeaux France |
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| Abstract: | The action of high doses of oestradiol on ovum implantation and decidual reaction was studied in pseudo-pregnant rats. It is shown that anomalies of ovum implantation take place after the injection of 10 μg of oestradiol on the 4th day of pregnancy, in that the decidual reaction is inhibited as demonstrated by ponderal evolution, lower 3H uridine uptake, ultrastructural features and the ploidy level of stromal cell nuclei. |
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